Skip to content

Butcher Research Group

Discovering novel nematode natural products and exploring their role in chemical communication

  • Home
  • Research
  • Our Group
    • Current Members
    • Past Members
    • Open Positions
  • Publications
  • News
  • Contact Us
  • Menu
We’ve moved

We’ve moved

In May 2017, we moved into our new lab space on the third floor of Joseph H. Hernandez Hall, the beautiful new Chemical Biology building that was recently completed at the University of Florida.
Shou Q., Feng L., et al.

Shou Q., Feng L., et al.

Check out our new paper in Nature Chemical Biology that describes “nemamide,” the first polyketide-nonribosomal peptide natural product discovered in an animal species. Read more →
Zhang X., et al.

Zhang X., et al.

Check out our new paper in PNAS that describes the structural basis for the substrate specificity of the acyl-CoA oxidases, enzymes that play an important role in C. elegans pheromone biosynthesis. Read more →
< >
Natural Product Discovery

Natural Product Discovery

We are using new techniques in comparative metabolomics, activity-guided fractionation, and NMR spectroscopy to identify the chemical structures of new pheromones and hormones from nematodes. Read more →
Natural Product Biosynthesis

Natural Product Biosynthesis

We are using CRISPR-Cas9, RNAi, comparative metabolomics, stable-isotope labeling, enzyme assays, and X-ray crystallography to discover how nematodes biosynthesize hormones and pheromones. Read more →
Natural Product Mechanism

Natural Product Mechanism

We are using chemical probes, transgenic worm strains, and biological assays to investigate how hormones and pheromones affect the development and behavior of nematodes. Read more →
Copyright © 2021 Butcher Research Group All Rights Reserved.
Catch Everest Theme by Catch Themes