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Butcher Research Group

Discovering novel nematode natural products and exploring their role in chemical communication

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Butcher Group 2025

Butcher Group 2025

In front of Scott Family Hall
We’ve moved

We’ve moved

In May 2017, we moved into our beautiful new lab space on the third floor of Scott Family Hall.
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Natural Product Discovery

Natural Product Discovery

We are using new techniques in comparative metabolomics, activity-guided fractionation, and NMR spectroscopy to identify the chemical structures of new pheromones and hormones from nematodes.
Natural Product Biosynthesis

Natural Product Biosynthesis

We are using CRISPR-Cas9, RNAi, comparative metabolomics, stable-isotope labeling, enzyme assays, and X-ray crystallography to discover how nematodes biosynthesize hormones and pheromones.
Natural Product Mechanism

Natural Product Mechanism

We are using chemical probes, transgenic worm strains, and biological assays to investigate how hormones and pheromones affect the development and behavior of nematodes.

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